HEM(1D) — Silicon Graphics
NAME
hem − three dimensional display of the Cytochrome P450 protein molecule
SYNOPSIS
/usr/people/demos/hem
DESCRIPTION
Dr. Tom Poulos and Prof. Joseph Kraut of the University of California at San Diego have constructed a computer model of the Cytochrome P450 molecule to aid in their research into the structure of this enzyme. Computer graphics help in comparing electron density maps to the proposed protein structure by moving the hypothetical structure into regions of high electron density. Proximity of atoms provides information regarding chemical interaction.
Hem displays the Cytochrome protein with control of viewing transformations via pop-up menu selections. Also, display of various parts of the protein molecule can be toggled on and off.
Pop the menu up by holding down the right mouse button. Menu selections are are toggled by placing the cursor atop the menu selection and pressing the left mouse button. The menu disappears when the right mouse button is released.
| Commands | |
| Item | Function |
| 1 | The hem group, the sub-unit which accepts and donates electrons |
| 2 | Van der Waal surface of the hem group |
| 3 | Electron density contour around the iron atom |
| 4 | Backbone of P450, connecting alpha-carbons of amino acid subunits |
| 5 | Amino acids that interact with the hem group |
HARDWARE REQUIREMENTS
A minimum configuration of 8 bitplanes and 1.5 Megabytes of memory is required to run hem.
Version 2.3 — July 04, 1985